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GPI — IFNG

Text-mined interactions from Literome

Fernandes et al., Immunology 2000 (Sporotrichosis) : Stimulation of murine M phi with interferon-gamma (IFN-gamma) induced NO production and inhibition of fungal growth
Haskó et al., Immunology 2001 : In the present study, we investigated the effect of sulphasalazine and two related compounds - sulphapyridine and 5-aminosalicylic acid - on M phi activation induced by bacterial lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma)
Kwan et al., Infect Immun 1992 : These findings indicate that at least one mechanism by which Leishmania infection attenuates the activation of M phi by IFN-gamma involves selective, transcriptional inhibition of major histocompatibility complex class II genes via a cAMP independent mechanism
Jaffar et al., J Immunol 2007 (Asthma...) : In vitro studies showed that PGI ( 2 ) did not affect IL-4 and IL-5 production or the level of IFN-gamma by the T cells
Stenger et al., Eur J Immunol 1991 (Leishmaniasis) : Consistent with the conclusion that endogenously produced TNF-alpha accounts for the synergism of IL 4 with IFN-gamma is the finding that N omega-monomethyl-L-arginine, an inhibitor of the L-arginine dependent generation of microbicidal nitrogen intermediates, totally blocked the M phi activation induced by IFN-gamma combined with IL 4 as well as by IFN-gamma combined with TNF-alpha
Keller et al., Eur J Immunol 1990 : Binding of high- and low-affinity IgG as well as expression of MHC class II molecules and of tumoricidal activity by BMM phi was markedly enhanced by rat interferon-gamma in low concentration ( 0.1 to 1.0 IU IFN-gamma/ml )
Stout et al., J Immunol 1989 : IFN-gamma, in the absence of LPS, could activate the elicited M phi and to a lesser and more variable degree, the resident M phi Only the M phi-c consistently required both IFN-gamma and LPS for induction of cytostatic activity ... TH2 could activate the Ag-presenting M phi-c in the presence of IFN-gamma
Radzioch et al., J Immunol 1988 : In contrast, neither H-7 nor retinal inhibited the activation of cytotoxic M phi by IFN-gamma , indicating that IFN-gamma acts through a PK-C independent pathway
Wilson et al., Infect Immun 1985 : These findings are consistent with an important role for IFN-gamma in the control of Toxoplasma infection and indicate that the anti-Toxoplasma activity of resting and IFN-gamma activated adult and neonatal M phi is similar
Boraschi et al., J Immunol 1984 : However, M phi-suppressive activity could be partially or completely reduced by in vitro pre-exposure to nonimmune IFN-alpha or immune recombinant IFN-gamma ... Furthermore, at variance with IFN-alpha, IFN-gamma directly stimulated M phi to synthesize and release IL 1, a monokine known to promote lymphocyte proliferation
Boraschi et al., Eur J Immunol 1984 (Neoplasms, Experimental) : In fact, at high doses IFN-gamma could also induce significant levels of both cytolytic and cytostatic activity in M phi of A/J and P/J mice, although it could not increase cytotoxic activities of C3H/HeJ M phi
Blasi et al., J Immunol 1984 : These results indicate that the activation of pM phi by IFN-gamma is independent of new protein synthesis, whereas the activation of pM phi by IFN-alpha and/or IFN-beta requires active protein synthesis, suggesting that the mechanism of induction of cytotoxic pM phi by IFN-gamma differs from that by the other types of IFN
Yang et al., Mol Immunol 1995 : cDNAs containing sequences which did not match published sequences were used to probe Northern blots prepared from both unstimulated and IFN-gamma activated GM-CSF- and CSF-1 derived m phi
Theus et al., Toxicol Appl Pharmacol 1993 : Although control animals showed a typical pattern of requiring both interferon (IFN)-gamma and lipopolysaccharide (LPS) for m phi activation, m phi from propanil treated animals were cytotoxic when induced with LPS alone
Heise et al., J Virol 1995 (Cytomegalovirus Infections...) : We conclude that ( i ) M phi activation is a prominent part of inflammatory responses to herpesvirus infection and ( ii ) IFN gamma and TNF alpha play a critical role in both virus induced M phi activation and control of herpesvirus growth independent of T and B cells
Beaman et al., J Immunol 1994 : These data taken together suggest that IL-6 enhances intracellular replication of T. gondii and reverses IFN-gamma mediated activation of murine peritoneal M phi , and that certain of the interactions between these two cytokines may be at the level of TNF-alpha triggering
Ohyama et al., No To Shinkei 1993 (Glioma) : These findings suggest that IFN-gamma augments the in vitro tumoricidal activation of M phi ; This effect appears to be unrelated to any influence of IFN-gamma on target sensitivity to lysis by macrophages
Redmond et al., J Immunol 1993 (Candidiasis) : IFN-gamma enhanced KC and PM phi candidacidal activity
Ayala et al., J Surg Res 1993 (Hemorrhage) : The results indicated that IFN-gamma restored the capacity of splenic M phi to mobilize [ Ca+2 ] i in response to FMLP
Wen et al., Cell Biol Int 1997 : LPS, IL-1 beta and TNF alpha effectively enhanced BK-stimulated production of PGI2 by HPASMC, while IFN gamma had only a weak effect on BK-stimulated PGI2 production
Heise et al., Virology 1998 (Herpesviridae Infections) : Infection of normal M phi with MCMV at a low m.o.i. ( 0.1 to 0.2 ) impaired IFN gamma mediated induction of M phi MHC class II expression, but not MHC class I expression
Goñalons et al., J Immunol 1998 : Therefore, IFN-gamma regulates the expression of MHC class II molecules at the translational level in both B cells and M phi and, as already reported, at the transcriptional level only in M phi