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CA1 — TNF
Text-mined interactions from Literome
Meldrum et al., J Surg Res 2003
(Myocardial Ischemia) :
We hypothesized that
CAB with cardiopulmonary bypass ( `` on-pump '' ) activates human myocardial NF-kappaB and
increases TNF in the heart
Ju et al., Eur J Cancer 2012
(Arthritis, Experimental...) :
The results showed that
CAI could
inhibit tumour necrosis factor-a (TNF-a) production in macrophages in various environments, including those isolated from peritoneal cavity of adjuvant induced arthritis ( AA ) rats, from Lewis lung carcinoma ( LLC ) transplanted tumours and those induced by LLC cells in vitro ... Over all, we found
CAI could act on macrophages and
regulate the production of
TNF-a not only in inflammatory diseases but also in tumour microenvironment, which might be another anti-tumour mechanism of CAI
Turpin et al., J Leukoc Biol 1990
:
TNF release ( L929 cytolytic assay ) in the
presence of
cAB occurred during the first 3 days of in vitro culture
Guo et al., J Pharmacol Exp Ther 2012
(Colitis...) :
CAI inhibited the production of
TNF-a , IL-1ß, and IL-6 in serum, supernatant of peritoneal macrophages, and lamina propria
Yamato et al., Blood 1989
:
TNF did not
increase Cai++ and, moreover, was able to stimulate accumulation of GM-CSF mRNA in the absence of extracellular Ca++ ... Our studies show that
TNF appears to increase levels of GM-CSF mRNA
independent of protein kinase C activity or levels of
Cai++
Watanabe et al., J Biochem 1996
:
These results indicate that the transient increase of [
Ca]i plays a role in LPS induced expression of
TNF-alpha by the macrophage cell line
West et al., Shock 1998
:
We sought to determine whether
carbonic anhydrase inhibition with acetazolamide would
prevent CO2 mediated inhibition of LPS stimulated
TNF release