Gene interactions and pathways from curated databases and text-mining

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CDKN1A — OPN1LW

Text-mined interactions from Literome

Snowden et al., Mol Cell Biol 2000 : Here we demonstrate that transcriptional activation by both p300 and CBP is stimulated by coexpression of the cyclin dependent kinase inhibitor p21 ( WAF/CIP1 )
Scolnick et al., Cancer Res 1997 (Breast Neoplasms) : Furthermore, CBP and P/CAF enhanced the ability of p53 to activate expression of the endogenous p21 ( cip1/waf1 ) gene, whereas E1A and dominant negative CBP mutants suppressed p53 dependent p21 ( cip1/waf1 ) expression
Kawasaki et al., Nature 1998 : Similarly, retinoic-acid induced transcriptional upregulation of the cell-cycle inhibitor p21Cip1 required normal levels of p300, but not CBP , whereas the reverse was true for p27Kip1