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IRS1 — MYLIP

Text-mined interactions from Literome

La Rocca et al., J Cell Physiol 2009 (Colonic Neoplasms) : We show here that an IRS-1 lacking its 3 ' UTR is no longer down-regulated by miR145 and rescues colon cancer cells from miR145 induced inhibition of growth ... These and other results, taken together, indicate that down-regulation of IRS-1 plays a significant role in the tumor suppressor activity of miR145
Jeong et al., Biochem Biophys Res Commun 2013 : The induction of miR-96 by mitochondrial dysfunction causes impaired glycogen synthesis through translational repression of IRS-1 in SK-Hep1 cells ... Furthermore, the ectopic expression of miR-96 caused a substantial decrease in IRS-1 protein expression, and a consequent impairment in insulin signaling