◀ Back to BCL2

BCL2 — PTK2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: Complex of PXN-BCL2-PTK2-PXN-PTK2-BCL2-PTK2-PXN-BCL2 (in vivo) Sorenson et al., Dev Dyn 1999*

Text-mined interactions from Literome

Hu et al., Breast Cancer Res Treat 2001 (Breast Neoplasms) : Our results suggest that PTK , PKC, P13-K and MEK signaling pathways can regulate Bcl-2 expression and form an integrated network that plays a critical role in cell survival
Murakami et al., Ann Surg Oncol 2011 (Carcinoma, Hepatocellular...) : PTK/ZK enhanced the IFN/5-FU induced apoptosis, based on increased proteins levels of Bax and reduced Bcl-xL and Bcl-2 ... PTK/ZK enhanced the IFN/5-FU induced apoptosis, based on increased proteins levels of Bax and reduced Bcl-xL and Bcl-2
Tatebe et al., Oncol Rep 1997 : Incubating the cells with genistein, a protein tyrosine kinase inhibitor, inhibited the taxol induced modified Bcl-2 expression and apoptosis
Chen et al., Oncogene 1997 : Here we demonstrate that v-Abl PTK activation is followed by an approximately twofold increase in mRNA level of Bcl-XL by 6 h and a corresponding increase in Bcl-XL protein level by 24 h. Bcl-xL RNA and protein decreased in IL-3 deprived cells in the absence of v-Abl PTK activity