Gene interactions and pathways from curated databases and text-mining

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BMI1 — TERT

Text-mined interactions from Literome

Dimri et al., Cancer Res 2002 (Breast Neoplasms...) : Overexpression of Bmi-1 in MECs led to activation of human telomerase reverse transcriptase ( hTERT ) transcription and induction of telomerase activity ... Telomerase induction by Bmi-1 was an early event in the extension of the replicative life span and immortalization
Song et al., Cancer Res 2006 (Disease Progression...) : Overexpression of Bmi-1 in NPECs led to the induction of human telomerase reverse transcriptase activity and reduction of p16(INK4a) expression
Fan et al., Biochim Biophys Acta 2008 (Prostatic Neoplasms) : Ectopic Bmi1 enhanced the expression of human telomerase reverse transcriptase ( hTERT ) and suppressed the exression of p16(INK4A) and p14(ARF) in CaP cells