Gene interactions and pathways from curated databases and text-mining

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HSPB3 — IGF1

Text-mined interactions from Literome

Ricort et al., FEBS Lett 2002 (Breast Neoplasms...) : Insulin-like growth factor binding protein-3 increases intracellular calcium concentrations in MCF-7 breast carcinoma cells
Bochinski et al., Int J Impot Res 2004 : Effect of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 complex in cavernous nerve cryoablation ... Effect of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 complex in cavernous nerve cryoablation
Santer et al., Cancer Res 2006 (Bone Neoplasms...) : Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome dependent proteolysis
Jerome et al., Cancer Res 2006 (Breast Neoplasms) : Recombinant human insulin-like growth factor binding protein 3 inhibits growth of human epidermal growth factor receptor-2 overexpressing breast tumors and potentiates herceptin activity in vivo
Oh et al., Mol Cancer Ther 2006 (Lung Neoplasms...) : Antimetastatic activity of insulin-like growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor independent urokinase-type plasminogen activator inhibition
Kawasaki et al., Neoplasia (New York, N.Y.) 2007 (Adenocarcinoma...) : Insulin-like growth factor binding protein 3 ( IGFBP3 ), which is induced by wild-type p53, regulates IGF and interacts with the TGF-beta pathway
von der Thüsen et al., Am J Pathol 2011 (Atherosclerosis...) : M1-polarized, macrophage conditioned medium inhibited IGF-1 signaling by ablating IGF-1 and increasing IGF binding protein 3 , increased vSMC apoptosis, and decreased proliferation
Villafuerte et al., Mol Endocrinol 1996 : Insulin and insulin-like growth factor-I regulate hepatic insulin-like growth factor binding protein-3 by different mechanisms