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CDK2 — GTF2B

Text-mined interactions from Literome

Ammosova et al., Retrovirology 2006 (Disease Progression...) : We also showed that CDK2 induces HIV-1 transcription in vitro and that inhibition of CDK2 expression by RNA interference inhibits HIV-1 transcription and viral replication in cultured cells
Debebe et al., Virology 2007 : Our recent studies showed that CDK2 participates in HIV-1 transcription and viral replication suggesting that inhibition of CDK2 by iron chelators might also affect HIV-1 transcription ... In conclusion, our findings add to the evidence that iron chelators can inhibit HIV-1 transcription by deregulating CDK2 and CDK9
Debebe et al., Mol Pharmacol 2011 : Tat itself is phosphorylated by CDK2 , and inhibition of CDK2 by small interfering RNA, the iron chelator 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone ( 311 ), and the iron chelator deferasirox ( ICL670 ) inhibits HIV-1 transcription
Breuer et al., Retrovirology 2012 : CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90 ... Our data indicate that CDK2 phosphorylates CDK9 on Ser 90 and thereby contributes to HIV-1 transcription