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CTSD — TP53

Text-mined interactions from Literome

Sun et al., Mol Carcinog 1999 (Neoplasm Metastasis) : p53 transcriptionally activates expression of the genes encoding epidermal growth factor receptor, matrix metalloproteinase (MMP)-2, cathepsin D , and thrombospondin-1 but represses expression of the genes encoding basic fibroblast growth factor and multidrug resistance-1
Iacobuzio-Donahue et al., Int J Oncol 2004 (Colorectal Neoplasms...) : However, differential regulation of cathepsin D expression by mutant versus wild-type p53 may also contribute to variable cathepsin D levels in colorectal cancers
Charpin et al., Hum Pathol 1995 (Breast Neoplasms) : The p53 tumor expression was independent of patient age, tumor size, axillary lymph node status, HER-2/neu and cathepsin D expression, and nuclear morphometric parameters