Gene interactions and pathways from curated databases and text-mining

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EPHB2 — NPS

Text-mined interactions from Literome

Yamahara et al., Proc Natl Acad Sci U S A 2003 (Inflammation...) : NPs significantly stimulated capillary network formation of cultured endothelial cells by cGK stimulation and subsequent Erk12 activation
Davey et al., Endocrinology 2012 (Hyperparathyroidism...) : In the current study, we determined the effects of the calcimimetics, NPS-R568 or cinacalcet, and the calcilytic, NPS-2143, on Ca ( o ) ( 2+ ) -mediated intracellular Ca ( 2+ ) mobilization, ERK1/2 phosphorylation, and plasma membrane ruffling in a stably transfected human embryonic kidney 293-TREx c-myc-CaSR cell line and applied a novel analytical model to quantify these modulator effects
Gehrke et al., Nanotoxicology 2013 (Colonic Neoplasms...) : The results indicate further that effects of SiO2 NPs are not mediated by oxidative stress but by interference with the MAPK/ERK1/2 as well as the Nrf2/ARE signalling pathways
Karlson et al., Methods 2013 : Herein, we investigate whether PS-NPs also activate ERK in DC in vitro