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EPHB2 — PDGFC
Text-mined interactions from Literome
Midgley et al., J Biol Chem 2004
:
Fibroblast growth factor-2 induction of
platelet derived growth factor-C chain transcription in vascular smooth muscle cells is
ERK dependent but not JNK dependent and mediated by Egr-1 ... Moreover, using pharmacological inhibitors we demonstrate the critical
role of
ERK but not JNK in FGF-2-inducible
PDGF-C expression ... These findings thus demonstrate that
PDGF-C transcription, activated by FGF-2, is
mediated by Egr-1 and its upstream kinase
ERK
Gebhard et al., Basic Res Cardiol 2010
:
PD98059, a specific inhibitor of
ERK phosphorylation, but not the p38 inhibitor SB203580 or the JNK inhibitor SP600125
prevented PDGF-CC induced TF expression in a concentration dependent manner ... PDGF receptor alpha and PDGF receptor beta inhibition prevented
PDGF-CC induced
ERK phosphorylation
Seikrit et al., Nephrol Dial Transplant 2013
:
Both PDGF-AA and
PDGF-CC induced phosphorylation and activation of extracellular signal regulated kinase 1 ( ERK1 ) and
ERK2