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CD19 — PTK7

Text-mined interactions from Literome

Fujimoto et al., Immunity 2000 : CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification
Xiao et al., J Biol Chem 1996 : We demonstrate that the CD19 receptor associates with the beta1 family integrin receptors on human B-cell precursors as well as mature B-lymphocytes, and engagement of the beta1 family integrin receptors with monoclonal antibody homoconjugates leads to rapid activation of the CD19 associated protein-tyrosine kinases ( PTK ) and results in hyperphosphorylation of CD19 on tyrosine residues ... Our findings prompt the hypothesis that homoconjugate induced integrin clustering may effect the approximation and, by intermolecular cross-phosphorylation, activation of the CD19 associated PTK and subsequent tyrosine phosphorylation of the CD19 receptor