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FUT4 — IL6

Text-mined interactions from Literome

Sugita et al., Res Commun Mol Pathol Pharmacol 1999 : We investigated the effect of FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines, interleukin-6 (IL-6) and interleukin-8 (IL-8), by monocytes stimulated with lipopolysaccharide (LPS) ... We investigated the effect of FUT-175 , a serine protease inhibitor, on the production of pro-inflammatory cytokines, interleukin-6 (IL-6) and interleukin-8 (IL-8), by monocytes stimulated with lipopolysaccharide (LPS) ... The productions of both IL-6 and IL-8, measured by enzyme linked immunosorbent assay, were significantly inhibited by FUT at the concentration of 1 to 100 microg/ml in a dose dependent manner ... Furthermore, the expressions of IL-6 and IL-8 mRNAs were also inhibited by FUT-175
Yu et al., Cell Immunol 2006 : We found that Hyper-IL-6 promoted the generation of CD15 ( + ) granulocytic and CD14 ( + ) monocytic cells and suppressed that of CD14 ( - ) CD1a ( + ) dendritic cells from CD36 ( - ) CD15 ( - ) CD14 ( - ) CD1a ( - ) IL-6R ( + ) myeloid progenitors
Yamamura et al., Cancer Sci 2007 : When CD34 ( + ) CD38 ( - ) hematopoietic progenitors were cultured with stem cell factor, flt3 ligand, thrombopoietin and IL-3, Delta-1, in combination with the IL-6R/IL-6 fusion protein FP6, increased the generation of glycophorin A ( + ) erythroid cells but counteracted the effects of IL-6 and FP6 on the generation of CD14 ( + ) monocytic and CD15 ( + ) granulocytic cells