Li et al., J Cell Biochem 2002
:
Surprisingly, the binding of GST-FKBP51 to calcineurin was FK506 independent and independent of a requirement for calcium or exogenous calmodulin Peattie et al., Proc Natl Acad Sci U S A 1992
:
hFKBP52 contains 12 protein kinase phosphorylation-site motifs and a potential calmodulin binding site, implying that posttranslational phosphorylation could generate multiple isoforms of the protein and that calmodulin and intracellular Ca2+ levels could affect FKBP52 function
Edlich et al., J Biol Chem 2006
(Brain Ischemia...) :
Here we show that neurotrophic FKBP ligands, such as GPI1046 and N- [ methyl ( ethoxycarbonyl ) ] cycloheximide, inhibit the calmodulin/Ca ( 2+ ) ( CaM/Ca(2+) ) -regulated FKBP38 with up to 80-fold higher affinity than FKBP12
Maestre-MartÃnez et al., Biol Chem 2010
:
To control Bcl-2 activity, FKBP38 requires a prior interaction with the Ca ( 2+ ) -sensor calmodulin (CaM)