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CAMKK1 — PRKAG1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Jensen et al., Am J Physiol Endocrinol Metab 2007
:
Possible
CaMKK dependent regulation of
AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction
Witczak et al., Diabetes 2007
:
The objective of this study was to determine whether
CaMKKalpha regulates skeletal muscle glucose uptake, and whether it is
dependent on
AMPK and/or Akt activation
Jensen et al., Am J Physiol Endocrinol Metab 2007
(Calcium Signaling) :
We conclude that a SR Ca ( 2+ ) -activated
CaMKK may
control alpha ( 1 )
-AMPK activation and be necessary for caffeine stimulated glucose uptake in mouse soleus muscle
Shen et al., Am J Physiol Cell Physiol 2007
:
In addition, ALA treatment
increased the association of
AMPK with
CaMKK ... To further show the
role of
CaMKK in
AMPK activation, short interfering RNA was used to silence CaMKK, which abolished the ALA induced AMPK activation
Mount et al., Atherosclerosis 2008
:
Bradykinin stimulates endothelial cell fatty acid oxidation by
CaMKK dependent
activation of
AMPK ... In conclusion, BK stimulates endothelial cell fatty acid oxidation by
CaMKK dependent activation of
AMPK
Jorgensen et al., Frontiers in bioscience : a journal and virtual library 2008
:
Specifically, the role of LKB1 and phosphatase PP2C in nucleotide dependent activation of AMPK, and ionized calcium in
CaMKK dependent
activation of
AMPK in working muscle is discussed
Thors et al., Biochim Biophys Acta 2008
:
In contrast, under culture conditions that do not facilitate a fall in ATP after stimulation,
AMPK activation is exclusively
mediated by
CaMKK and does not contribute to the phosphorylation of eNOS
Lee et al., Bone 2010
(Bone Resorption) :
AMPK negatively
regulates RANKL, possibly by acting through
CaMKK and TAK1
Hsu et al., J Pharmacol Exp Ther 2011
:
7H-benz [ de ] benzimidazo [ 2,1-a ] isoquinoline-7-one-3-carboxylic acid acetate ( STO-609 ), a calmodulin kinase kinase ( CaMKK ) inhibitor, reduced the level of expression of CYP4F2 elicited by genistein, suggesting that
CaMKK activation
contributed to
AMPK activation by genistein
Kawashima et al., PloS one 2012
(Hypoglycemia) :
However, the
involvement of
CaMKK in neuroglucopenia induced activation of
AMPK in the hypothalamus has not been tested ... To determine whether neuroglucopenia induced
AMPK activation is
mediated by
CaMKK , we tested whether STO-609 ( STO ), a CaMKK inhibitor, would block the effects of 2-deoxy-D-glucose ( 2DG ) -induced neuroglucopenia both ex vivo on brain sections and in vivo ... In conclusion, activation of hypothalamic
AMPK by 2DG induced neuroglucopenia is not
mediated by
CaMKK
Morotomi-Yano et al., Biochem Biophys Res Commun 2012
:
In LKB1-deficient cells,
AMPK activation by nsPEFs was
mediated by
CaMKK and required extracellular Ca ( 2+ ), which suggested the occurrence of Ca ( 2+ ) mobilization and its participation in AMPK activation by nsPEFs