Gollmer et al., Blood 2009
:
CCL21 costimulation resulted in increased Ras- and Rac-GTP formation and enhanced phosphorylation of Akt, MEK, and ERK but not p38 or JNK
Xu et al., PloS one 2011
(Carcinoma, Non-Small-Cell Lung...) :
LY294002, a selective inhibitor of PI3K that prevents activation of the downstream Akt, did not weaken the effect of CCL21/CCR7 on P-ERK