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GRAP2 — IL3

Text-mined interactions from Literome

Birkenkamp et al., Eur Cytokine Netw 1999 (Acute Disease...) : Despite the fact that IL-3 did induce p38 and ERK kinase activity, it was not able to enhance IL-6 protein secretion, which coincided with the inability of IL-3 to induce NFkappaB ( nuclear factor kappaB ) activation and IkappaB ( inhibitory protein kappaB ) degradation
Ling et al., Crit Care Med 2002 : In contrast to its effects on the janus kinase/STAT pathways, interleukin-6 activation of MAP kinases ( extracellular signal regulated kinase-1, extracellular signal regulated kinase-2, and p38 ) was unaffected by endotoxin
Zirngibl et al., Mol Cell Biol 2002 : Bone marrow derived Fps/Fes-null macrophages showed no defects in granulocyte-macrophage colony stimulating factor-, interleukin 6 (IL-6)-, or IL-3 induced activation of signal transducer and activator of transcription 3 ( Stat3 ) and Stat5A or LPS induced degradation of I kappa B or activation of p38 , Jnk, Erk, or Akt
Yan et al., J Biol Chem 2002 : This model probiotic also inhibits activation of the pro-apoptotic p38/mitogen activated protein kinase by tumor necrosis factor, interleukin-1alpha , or gamma-interferon
Wheadon et al., Blood 2003 : Induction of TEL/PDGFbetaR expression led to increased cell survival following IL-3 withdrawal and constitutive activation of protein kinase B (PKB), signal transducer and activator of transcription 5 ( STAT5 ), extracellular signal regulated kinases 1/2 ( ERK1/2 ), Jun N-terminal kinases 1/2 (JNK1/2), and p38 mitogen activated protein kinase ( MAPK ) pathways
Rasheed et al., Arthritis Res Ther 2010 (Osteoarthritis) : Pomegranate extract inhibits the interleukin-1ß induced activation of MKK-3, p38a-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes