Gene interactions and pathways from curated databases and text-mining

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CNP — IL1B

Text-mined interactions from Literome

Murakami et al., Am J Physiol Lung Cell Mol Physiol 2004 (Pulmonary Fibrosis) : Interestingly, CNP markedly reduced bronchoalveolar lavage fluid IL-1beta levels
Jana et al., Free Radic Biol Med 2005 (Encephalomyelitis, Autoimmune, Experimental...) : Interestingly, both IL-1beta and TNF-alpha markedly inhibited the expression of MOG, CNPase , and PLP but not MBP, the effect that was blocked by antioxidants such as N-acetylcysteine (NAC) and pyrrolidine dithiocarbamate ( PDTC )
Suga et al., Endocrinology 1993 : While interleukin (IL)-2 had no significant effect on CNP secretion, IL-1 alpha, IL-1 beta and tumor necrosis factor (TNF)-alpha stimulated CNP secretion in a time- and dose dependent manner