Kakuma et al., Endocrinology 2000
(Obesity) :
We conclude that leptin action is required for normal basal and cold stimulated PGC-1 expression in BAT in rodents and that hyperleptinemia rapidly up-regulates its expression, at least in part, by direct action
Gómez-Ambrosi et al., Mol Cell Endocrinol 2001
:
The aim of this study was to assess the acute effect of a beta ( 3 ) -adrenergic agonist ( Trecadrine ) and leptin on the expression of PGC-1 and PPARgamma2 mRNA in BAT