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GJC1 — VEGFA
Text-mined interactions from Literome
Suarez et al., J Cell Sci 2001
:
VEGF maximally
blocked GJC 15 minutes after growth factor administration ... The function of
VEGF mediated disruption of
GJC might be to restrict an increase in endothelium permeability to the environment affected by local injury to blood vessels
Thuringer et al., Ann N Y Acad Sci 2004
:
Dye coupling experiments revealed that BK or
VEGF completely
blocked GJC ... We conclude that
VEGF induced disruption of
GJC via Cx43 remodeling is relayed by an autocrine communication via secretion of ATP to preserve intercellular Ca ( 2+ ) signaling in capillary endothelium