Gene interactions and pathways from curated databases and text-mining

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IL13 — OLR1

Text-mined interactions from Literome

Bhattacharya et al., Tumour Biol 2009 (Adenoma...) : Regulation of 15-LOX-1 expression is achieved at transcription level by global histone acetylation and may also be dependent on GATA-6, IL-4 and IL-13
Hsi et al., Mol Cancer Ther 2011 (Glioblastoma) : We hypothesize that in GBM, IL-13 can induce 15-LOX-1 , which regulates cell apoptosis via signaling through PPAR? and that expression of IL-13Ra2 prevents apoptosis and contributes to tumor growth ... Knocking down IL-13Ra2 with short interfering RNA dramatically induces 15-LOX-1 expression, promotes apoptosis, and reduces GBM tumor growth in vivo