Gene interactions and pathways from curated databases and text-mining

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ANKH — MMP13

Text-mined interactions from Literome

Johnson et al., Osteoarthritis Cartilage 2004 (Calcinosis...) : Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess
Kim et al., Bone 2010 : In the presence of levamisole, a specific APase inhibitor to prevent hydrolysis of extracellular PP(i) to P ( i ), ANK overexpression of growth plate chondrocytes resulted in decreased mRNA levels of hypertrophic and terminal differentiation markers but increased MMP-13 mRNA levels