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EGF — MYC
Text-mined interactions from Literome
Nanba et al., J Cell Physiol 2008
(Fibrosarcoma) :
An intermediary role of
proHB-EGF shedding in growth factor
induced c-Myc gene expression ...
Induction of
c-Myc expression by
EGF or basic FGF is recovered in Hb-egf depleted MEFs by overexpression of wild-type proHB-EGF, but no recovery was observed with an uncleavable mutant of proHB-EGF
Lee et al., Nat Med 2010
(Intestinal Neoplasms...) :
MyD88 ( myeloid differentiation primary response gene 88 ) -independent activation of ERK by
epidermal growth factor (EGF) increased p-ERK and
c-Myc and restored the multiple intestinal neoplasia ( Min ) phenotype in Apc ( min/+ ) /Myd88 ( -/- ) mice
Yoshida et al., Jpn J Cancer Res 1990
(Carcinoma...) :
Both EGF and TGF-alpha stimulated EGFR phosphorylation,
EGF and TGF-alpha
induced FOS,
MYC and ERBB-2 oncogene expression
Yang et al., Cell 2012
(Astrocytoma...) :
PKM2 dependent histone H3 modifications are instrumental in
EGF induced expression of cyclin D1 and
c-Myc , tumor cell proliferation, cell-cycle progression, and brain tumorigenesis
Luo et al., J Biol Chem 1995
:
Coexpression of recombinant 14.3.3 with recombinant Myc tagged Raf in COS cells does increase substantially the Myc-Raf kinase activity achieved during transient expression, which is attributable primarily to an increased level of Myc-Raf polypeptide, without alteration of
Myc-Raf specific activity or the activation that occurs in
response to
epidermal growth factor or 12-O-tetradecanoylphorbol-13-acetate
Cowlen et al., Biochim Biophys Acta 1993
:
We now report the effects of HODEs and prostaglandins on
EGF dependent expression of the growth related
proto-oncogene c-myc in SHE cells