Gene interactions and pathways from curated databases and text-mining

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GINS4 — MCM2

Pathways - manually collected, often from reviews:

  • Reactome Reaction: MCM2 → GINS4 (indirect_complex)
  • Reactome Reaction: MCM2 → GINS4 (reaction)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: MCM2 — GINS4 (interaction, mapped from grid reactome mint intact)
  • STRING interaction: GINS4 — MCM2 (interaction, mapped from grid reactome mint intact)

Text-mined interactions from Literome

Dang et al., J Biol Chem 2011 : Here, we demonstrated that the CMG complex is formed in vivo in trypanosomes and that Mcm2-7 helicase activity is activated by the association with Cdc45 and the GINS complex in vitro
Bruck et al., J Biol Chem 2011 : Sld2 interaction with Mcm2-7 blocks the interaction between GINS and Mcm2-7