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HIF1A — MMP3

Text-mined interactions from Literome

Luo et al., BJU Int 2006 (Neoplasm Invasiveness...) : The expression of E-cadherin, vimentin, cathepsin D, MMP-2 and uPAR, which are proteins with established roles in the pathophysiology of invasion, could be regulated by HIF-1alpha in human prostate cancer cells
Ahn et al., Rheumatology (Oxford) 2008 (Arthritis, Rheumatoid) : Hypoxia induced MMP-3 expression is exclusively regulated by HIF-1alpha , and hypoxia induced MMP-1 or IL-8 expression appears to have salvage pathways other than the HIF-1alpha pathway
Lin et al., FEBS Lett 2008 (Osteoarthritis) : In vitro invasion assays and quantitative PCR analyses showed that targeted inhibition of HIF-1alpha in bmMSC-1 decreased its invasion and expressions of MMP1 and MMP3, whereas overexpression of HIF-1alpha in bmMSC-5 increased its invasion and expressions of MMP1 and MMP3 ... Therefore, HIF-1alpha can regulate MMP1 and MMP3 expressions in human bmMSCs, which might suggest a pathophysiological role of bmMSC expressing high HIF-1alpha in bone diseases
Kang et al., Clin Exp Pharmacol Physiol 2009 (Diabetes Mellitus, Experimental...) : Impairment of ischaemia induced EPC mobilization in the diabetic mouse model is associated with altered HIF-1 alpha/VEGF and MMP/TIMP regulation and represents a novel mechanism underlying defective postischaemic neovascularization in diabetes