Song et al., Endocrinology 2002
:
Moreover, BPA increased the activation of mitogen activated protein kinase Canesi et al., Aquat Toxicol 2005
(MAP Kinase Signaling System) :
In particular, BPA induced a dramatic decrease in phosphorylation of the stress activated p38 MAPK , whose activation is crucial in mediating the bactericidal activity
Park et al., J Reprod Dev 2009
(Ovarian Neoplasms) :
BPA rapidly induced activation of extracellular signal regulated kinase ( ERK ) 1/2 and p38 MAPK at 15 min, but the effect of BPA ( 10 microM ) on stimulation of cell growth was not blocked by pretreatment with inhibitors of MEK ( PD98059 ) or p38 ( SB203580 ) in a dose dependent manner