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IL6 — TFAP2A
Text-mined interactions from Literome
Oyama et al., J Invest Dermatol 1999
:
Co-incubation with neutralizing antibodies against various inflammatory cytokines resulted in inhibition of the
interleukin-6 dependent
activator protein-2 induction at varying degrees, indicating an involvement of various cytokines in the activator protein-2 induction
Gustafson et al., Biochem Biophys Res Commun 2003
:
Several observations showed that the adiponectin and aP2 genes can be differentially regulated in adipocytes : ( 1 ) Topiramate, an anti-epileptic agent with weight reducing properties, increased adiponectin mRNA levels and secretion, but did not, like the thiazolidinediones, increase aP2 expression ; ( 2 )
IL-6 reduced adiponectin, but significantly increased, aP2 expression ; and ( 3 ) TNFalpha
inhibited adiponectin, but paradoxically increased,
aP2 expression in PPAR gamma 2-infected C/EBP alpha null cells