Gene interactions and pathways from curated databases and text-mining

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PI3 — TBC1D4

Text-mined interactions from Literome

Bertola et al., J Biol Chem 2007 (Insulin Resistance) : We show here that in 3T3-L1 adipocytes HGF stimulates the phosphatidylinositol (PI) 3-kinase dependent protein kinase B (PKB) activity, AS160 phosphorylation, Glut4 translocation, and consequently, glucose uptake
Funai et al., Diabetes 2009 : These data suggest that 1 ) insulin stimulates glucose transport and phosphorylation of AS160 and TBC1D1 in a PI 3-kinase/Akt dependent manner, 2 ) contraction stimulates PAS-AS160 ( but not PAS-TBC1D1 or glucose transport ) in a PI 3-kinase/Akt dependent manner, and 3 ) contraction stimulates PAS-TBC1D1 and glucose transport ( but not PAS-AS160 ) in an AMPK dependent manner