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EGF — GP5
Text-mined interactions from Literome
Hayashida et al., Int J Mol Med 1999
:
EGF stimulated the mucus
glycoprotein synthesis which is characterized with cell maturation, but competed with HB-EGF for cell proliferation
Roberson et al., Mol Cell Biol 2000
(Choriocarcinoma...) :
Role of the cyclic AMP response element binding complex and activation of mitogen activated protein kinases in synergistic
activation of the
glycoprotein hormone alpha subunit gene by
epidermal growth factor and forskolin
Thway et al., Biol Reprod 2002
(Choriocarcinoma) :
An activator protein-1 complex mediates
epidermal growth factor regulation of equine
glycoprotein alpha subunit expression in trophoblast cells ... Previously, we have reported that
epidermal growth factor (EGF) regulates the equine
glycoprotein hormone alpha subunit promoter through a protein kinase C ( PKC ) /mitogen activated protein kinase ( MAPK ) signal transduction pathway in trophoblasts ... The current study investigates the regulatory element/factors involved in the
induction of equine
glycoprotein alpha subunit gene expression by
EGF
Chen et al., J Invest Surg 2002
(Hypertension, Portal) :
Our current study shows that the rate of incorporation of glucosamine is decreased in the PHT gastric mucosa and that
EGF significantly
stimulated glycoprotein synthesis in the PHT gastric mucosa
Montgomery et al., Prostate 1992
(Adenocarcinoma...) :
We have demonstrated that the PSA
glycoprotein is upregulated by androgens and is
affected by neither
epidermal growth factor nor basic fibroblast growth factor
Ye et al., Chin J Cancer 2004
(Glioma) :
Leucine-rich repeats and immunoglobulin-like domains 1 ( LRIG1 ) is a kind of transmembrane
glycoprotein , which is
induced by
epidermal growth factor (EGF) , and develops inhibitory negative feedback by specific binding with epidermal growth factor receptor (EGFR)
Kadowaki et al., J Biol Chem 1987
(Carcinoma, Squamous Cell) :
In the KB cells, using phosphotyrosine-specific antibody we have found that : the receptors for insulin ( beta subunit ), IGF-I ( beta subunit ), and EGF undergo tyrosine phosphorylation as early as 10 s after addition of their respective ligands ; a 185-kDa protein is rapidly ( less than 10 s ) tyrosine phosphorylated by insulin and IGF-I through their respective receptor kinases but not EGF ; tyrosine phosphorylation of a 190-kDa
glycoprotein is rapidly ( less than 10 s )
induced by
EGF through EGF receptor kinase ; and tyrosine phosphorylation of a 240-kDa protein is stimulated within 30 s by all three growth factors
Yoshida et al., In Vitro Cell Dev Biol 1987
:
Effect of biosynthetic human
epidermal growth factor on the synthesis and secretion of mucin
glycoprotein from primary culture of rabbit fundal mucosa cells ... Biosynthetic human
epidermal growth factor ( Bh-EGF )
induced dose dependent synthesis and secretion of neutral mucin
glycoprotein when the fundal cells isolated from rabbit stomach were cultured in serum-free medium containing Bh-EGF at concentrations as high as 10 to 100 ng/ml
Slomiany et al., J Physiol Pharmacol 1993
:
The binding of
EGF to buccal mucosal calcium channel receptor protein was also
inhibited ( 36-41 % ) by acidic mucus
glycoprotein
Chaidarun et al., Endocrinology 1994
(Pituitary Neoplasms) :
In contrast, the expression of
glycoprotein hormone common alpha-subunit gene in the tumor cells was
reduced by
EGF , T3, and 17 beta-estradiol
Tremblay et al., Gastroenterology 1997
:
The
effects of
EGF ( 1, 10, and 100 ng/mL ) on DNA synthesis,
glycoprotein synthesis, and lipase and pepsin activities in fetal gastric explants maintained in serum-free organ culture were determined
Solic et al., Exp Cell Res 1997
(Adenocarcinoma...) :
We have characterized the morphological
effects of
EGF on GP2d and
GP5d colon carcinoma cell lines and have compared the ability of the heparin binding EGF receptor ligand amphiregulin (AR) to elicit the same effects