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EGF — PHKA2

Text-mined interactions from Literome

Wang et al., J Biol Chem 1999 : However, the activation of the calcium-sensitive tyrosine kinase PYK2 , which occurred in response to angiotensin II, but not EGF , was inhibited by nitric oxide
Shah et al., Mol Pharmacol 2002 : Ang II increased the association of Pyk2 with Src and with the epidermal growth factor receptor (EGF-R) ... Ang II-induced activation of ERK, but not Pyk2 , was prevented by inhibition of EGF receptor phosphorylation by AG 1478 and of Src kinase by PP1
Frank et al., Mol Cell Biol 2003 : Dominant negative PYK2 inhibited H2O2 induced JAK2 activation but not EGF receptor activation, whereas dominant negative PKC-delta inhibited PYK2 activation by H2O2
Shi et al., J Biol Chem 2004 : Pyk2 is a member of the focal adhesion kinase family and can be activated by c-Src, epidermal growth factor receptor (EGFR), Janus kinase 1, tyrosine kinases, and G-protein coupled receptor signaling ... Expression of constructs for dominant negative forms of either Pyk2 or c-Src impair EGF induced Stat3 phosphorylation
Bermudez et al., Growth Factors 2008 (Ovarian Neoplasms) : Pyk2/ERK 1/2 mediate Sp1- and c-Myc dependent induction of telomerase activity by epidermal growth factor
Schauwienold et al., J Biol Chem 2008 : The ionomycin induced Pyk2 phosphorylation was partially sensitive to AG1478, heparin, or the matrix-metalloproteinase inhibitor BB2116, and the ionomycin induced EGF receptor phosphorylation was almost completely blocked by these inhibitors of extracellular transactivation
Block et al., Cell Signal 2011 : Extracellular ATP stimulates epithelial cell motility through Pyk2 mediated activation of the EGF receptor ... Disruption of Pyk2 signaling either by siRNA or by expression of a dominant negative mutant led to inhibition of ATP induced activation of the SFKs and the EGF receptor