UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to H2AFX

H2AFX — UBE2N

Pathways - manually collected, often from reviews:

NCI Pathway Database ATM pathway: MRN complex/ATM/MDC1/H2AX complex (MRE11A-NBN-RAD50-ATM-H2AFX-MDC1) → UBC13 (UBE2N) (modification, collaborate) Mailand et al., Cell 2007, Huen et al., Cell 2007, Kolas et al., Science 2007
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database ATM pathway: UBC13 (UBE2N) → MRN complex/ATM/MDC1/H2AX/RNF8 complex (MRE11A-NBN-RAD50-ATM-H2AFX-MDC1-RNF8) (modification, activates)
Mailand et al., Cell 2007, Huen et al., Cell 2007, Kolas et al., Science 2007
Evidence: mutant phenotype, assay, physical interaction