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DEFB114 — IL6
Text-mined interactions from Literome
Semple et al., Eur J Immunol 2010
(Endotoxemia...) :
In addition, in the presence of LPS, hBD3 and the murine orthologue
Defb14 ( but not hBD2 ), effectively
inhibit TNF-alpha and
IL-6 accumulation implying an anti-inflammatory function
Harvey et al., Scientific reports 2013
:
In murine JAWSII dendritic cells,
DEFB103 significantly
attenuated , yet rarely enhanced, the Cxcl2,
Il6 , and Csf3 responses to HagB ; and in C57/BL6 mice, DEFB103 significantly enhanced, yet rarely attenuated, the Cxcl1, Csf1, and Csf3 responses