Gene interactions and pathways from curated databases and text-mining

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IL2 — MRAP

Text-mined interactions from Literome

Gur et al., J Exp Med 1990 : Moreover, crosslinking native or truncated A2 or B27 induced IL-2 production upon co-stimulation with phorbol myristate acetate
Wong-Baeza et al., J Immunol 2013 (Spondylitis, Ankylosing) : B27 ( 2 ) and B27 FHC stimulated KIR3DL2CD3e transduced T cell IL-2 production to a greater extent than control HLA-class I. KIR3DL2 binding to B27 inhibited NK IFN-? secretion and promoted greater survival of KIR3DL2 ( + ) CD4 T and NK cells than binding to other HLA-class I. KIR3DL2 ( + ) T cells from B27 ( + ) SpA patients proliferated more in response to Ag presented by syngeneic APC than the same T cell subset from healthy and disease controls