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IRF6 — MET

Text-mined interactions from Literome

Li et al., Zhongguo Yao Li Xue Bao 1998 : Our studies showed that Met-Enk over a wide range of concentrations increased interleukin-1 (IL-1) production from mouse peritoneal macrophages induced by lipopolysaccharides (LPS) and naloxone did not block the enhancing effect
Huang et al., Life Sci 2006 : Ibudilast effectively blocks lipopolysaccharide (LPS) induced tumor necrosis factor ( TNFalpha, IC50 = 6.2 microM ) and N-formyl-Met-Leu-Phe ( fMLP ) -induced leukotriene (LT) B4 biosynthesis ( IC50 = 2.5 microM ) in human whole blood, which are 3 and 6-fold more potent than cilomilast, respectively
Zhao et al., Am J Physiol Lung Cell Mol Physiol 2013 : Pretreatment with a c-Met inhibitor ( PHA-665752 ) or inhibition of protein kinase C ( PKC ) -a attenuated the LPS mediated phosphorylation of c-Met and its internalization ... LPS induced c-Met tyrosine 1003 phosphorylation, activation of PKCa, and c-Met internalization were, however, reversed by pretreatment of cells with LPA, which increased c-Met accumulation at cell-cell contacts