◀ Back to IRF6

IRF6 — RSAD2

Text-mined interactions from Literome

Severa et al., J Biol Chem 2006 : LPS and poly ( I-C ) induce very high levels of Viperin in wild type cells but not in cells deficient in TRIF, TBK1, IRF3, or the type I IFNalpha/betaR
Stirnweiss et al., J Immunol 2010 (Vesicular Stomatitis) : In this study, we show that IRF-1 directly binds to the murine viperin promoter to the two proximal IRF elements and thereby induces viperin expression ... Further, IRF-1 , but not IFN type I, mediates the induction of viperin transcription after IFN-gamma treatment ... In contrast, IRF-1 is not required for IFN independent viperin induction by Newcastle disease virus infection and by infection with a vesicular stomatitis virus mutant that is unable to block IFN expression and secretion