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IGFBP1 — IL6

Text-mined interactions from Literome

Feliers et al., Br J Haematol 1999 (Multiple Myeloma) : In contrast, IGFBP4 was not regulated in response to IL-6 , TNF-alpha, PDGF BB, bFGF, TGF-beta or the cAMP agonist, forskolin
Lelbach et al., J Hepatol 2001 : In cocultures, biosynthesis of IGFBP-1 , -3 and -4 was increased dose-dependently by IL-6 , while the effects of IL-1beta or TNFalpha were less prominent
Pihl et al., Horm Res 2006 : Acute interleukin-6 infusion increases IGFBP-1 but has no short-term effect on IGFBP-3 proteolysis in healthy men ... These data suggest that moderately elevated levels of IL-6 such as in the post-operative state or after exercise may contribute to increased levels of IGFBP-1
Wang et al., Atherosclerosis 2012 (Carotid Artery Diseases) : In vitro studies showed that IL-1ß, IL-6 and TNFa stimulated IGFBP-1 mRNA expression in SMCs. IGFBP-1 stimulated SMC proliferation through ERK1/2 activation but independently of the IGF-1 receptor