Zhu et al., J Biol Chem 2004
:
Finally, 5-aza-CdR induced p21 ( Waf1/Cip1 ) expression was dependent on DNA damage but not on DNA demethylation as demonstrated by comet assay and bisulfite sequencing, respectively
Pulukuri et al., Int J Oncol 2005
(Prostatic Neoplasms) :
Finally, the comet or SCGE assay and methylation-sensitive restriction analysis demonstrated that 5-aza-CdR induced p53 and p21Waf1/Cip1 expression as a consequence of DNA damage and independent of DNA demethylation