◀ Back to EGF
EGF — PPARG
Text-mined interactions from Literome
Fuenzalida et al., J Biol Chem 2005
(Pheochromocytoma) :
We show that NGF but not
epidermal growth factor increases the transcriptional activity of
PPARgamma , and modulates the expression of this transcription factor
Olsen et al., Exp Cell Res 2006
(MAP Kinase Signaling System) :
It has earlier been shown that
epidermal growth factor (EGF) induces MAPK phosphorylation of
PPARgamma resulting in a less transcriptionally active receptor
Zhou et al., Lab Invest 2007
:
Our results in this report indicate that the activation of PDGF or
EGF signaling by exogenous PDGF or EGF
inhibits PPARgamma gene expression in passaged HSC
Lin et al., Lab Invest 2008
:
Further experiments observed that curcumin dose dependently reduced gene expression of PDGF and
EGF receptors ( ie, PDGF-betaR and EGFR ), which
required PPARgamma activation
Zaouali et al., Liver Transpl 2010
(Disease Models, Animal...) :
When AKT was inhibited, the
effects of
EGF and IGF-I on GSK3(beta),
PPAR gamma , hepatic injury and function disappeared