Gene interactions and pathways from curated databases and text-mining

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EGF — SLC25A3

Text-mined interactions from Literome

Chen et al., Mol Pharmacol 2006 : It is noteworthy that NSC-87877 inhibited epidermal growth factor (EGF) induced activation of Shp2 PTP , Ras, and Erk1/2 in cell cultures but did not block EGF induced Gab1 tyrosine phosphorylation or Gab1-Shp2 association
Chen et al., Biochem Pharmacol 2010 : Incubation of cells with SPI-112Me inhibited epidermal growth factor (EGF) stimulated Shp2 PTP activity and Shp2 mediated paxillin dephosphorylation, Erk1/2 activation, and cell migration
Su et al., J Biol Chem 1996 : These results suggest that, unlike in hematopoietic cells, PTP1C in 293 cells plays a positive role in epidermal growth factor- or serum activated mitogenesis