◀ Back to CDK2
CDC23 — CDK2
Pathways - manually collected, often from reviews:
-
KEGG Oocyte meiosis:
Complex of CCNE1-CCNE2-CDK2
→
ANAPC1/ANAPC10/ANAPC11/ANAPC13/ANAPC2/ANAPC4/ANAPC5/ANAPC7/CDC16/CDC23/CDC26/CDC27
(protein-protein, inhibition)
-
Reactome Reaction:
CDC23
→
CDK2
(reaction)
Lukas et al., Nature 1999, Sørensen et al., Mol Cell Biol 2001, Takahashi et al., Mol Cell 2012
-
Reactome Reaction:
CDC23
→
CDK2
(indirect_complex)
Lukas et al., Nature 1999, Sørensen et al., Mol Cell Biol 2001, Takahashi et al., Mol Cell 2012
Text-mined interactions from Literome
Heo et al., Curr Genet 1999
:
Hence, SCC1/MCD1/RHC21 is positively
regulated by the mitotic
CDK ,
CDC28
Li et al., Nat Cell Biol 2004
:
On exit from metaphase in Xenopus laevis egg extracts,
CDK dependent activation of the
anaphase promoting complex (APC/C) results in the transient polyubiquitination of geminin
Mitra et al., Cell cycle (Georgetown, Tex.) 2006
:
Dual
regulation of the
anaphase promoting complex in human cells by cyclin
A-Cdk2 and cyclin A-Cdk1 complexes
Ullah et al., Cell cycle (Georgetown, Tex.) 2009
(Polyploidy) :
The critical step, however, appears to be switching from a
CDK dependent form of the
anaphase promoting complex (APC) to one that functions only in the absence of CDK activity
Cocklin et al., PloS one 2011
:
Cell division is controlled in part by the timely
activation of the
CDK ,
Cdc28 , through its association with G1 and G2 cyclins
Jallepalli et al., Genes Dev 1996
:
Rum1 and
Cdc18 link
inhibition of
cyclin dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe
Sutton et al., Genetics 1997
:
The CAK1 gene encodes the major
CDK activating kinase (CAK) in budding yeast and is
required for activation of
Cdc28p for cell cycle progression from G2 to M phase
Zachariae et al., Science 1998
:
Control of cyclin ubiquitination by
CDK regulated binding of Hct1 to the
anaphase promoting complex