Gene interactions and pathways from curated databases and text-mining

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ABL1 — MAP3K1

Text-mined interactions from Literome

Kharbanda et al., Mol Cell Biol 2000 : Transient-transfection studies with wild-type and kinase-inactive c-Abl demonstrate c-Abl kinase dependent activation of MEKK-1 ... Moreover, c-Abl activates MEKK-1 in vitro and in response to DNA damage
Nawata et al., Oncogene 2003 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : These results indicate that MEKK1 is a downstream target of Bcr-Abl, and that the antiapoptotic effect of Bcr-Abl in chronic myelogenous leukemia cells is mediated via the MEKK1-NF-kappaB pathway
Nakamura et al., Oncogene 2005 (Cell Transformation, Neoplastic...) : Bcr-Abl enhanced MEKK1 expression in ES transfectants, as it does in other Bcr-Abl transformed cells