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CDKN1A — MET

Text-mined interactions from Literome

Brosh et al., Cell Death Differ 2013 : Finally, we demonstrate that the inhibitory effect of p53 on MET is mediated by p21
Storozhuk et al., Br J Cancer 2013 (Carcinoma, Non-Small-Cell Lung...) : Ionising radiation and MET induced ( i ) sustained activation of ATM-AMPK-p53/p21 ( cip1 ) and inhibition of Akt-mTOR-4EBP1 pathways in tumours, ( ii ) reduced expression of angiogenesis and ( iii ) enhanced expression of apoptosis markers.Conclusion : Clinically achievable MET doses inhibit NSCLC cell and tumour growth and sensitise them to IR