Gene interactions and pathways from curated databases and text-mining

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ITGB3 — PI3

Text-mined interactions from Literome

Greenwood et al., J Cell Biol 2000 : Further evidence demonstrated that activation of PI 3-kinase by PDGF induced a decrease in the association of alpha-actinin with the integrin beta subunit, and that PtdIns ( 3,4,5 ) -P ( 3 ) could disrupt this interaction in vitro
Vellon et al., Mol Carcinog 2006 (Breast Neoplasms...) : Here, we have assessed the role of the extracellular signal regulated kinase ( ERK1 ) /ERK2, mitogen activated protein kinase ( MAPK ), and phospoinositide 3-kinase (PI-3'K) signaling pathways in the expression and function of alpha(v)beta(3) integrin in breast cancer models