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ADAM12 — TNF

Text-mined interactions from Literome

Schlomann et al., J Neurosci 2000 (Heredodegenerative Disorders, Nervous System) : In primary astrocytes from wild-type and WR mice, in primary cerebellar neurons, and in mouse motoneuron-like NSC19 cells, ADAM8 expression was induced up to 15-fold by mouse TNF-alpha , in a dose dependent manner ... In both cell types, ADAM8 was also induced by human TNF-alpha , indicating that TNF receptor type I ( p55 ) is involved
Bzowska et al., Eur J Biochem 2004 : Therefore, ADAM17 dependent depletion of membrane bound tumor necrosis factor receptors from endothelial cells might constitute a mechanism of self-protection in states of prolonged immunostimulation
Estrella et al., Am J Respir Cell Mol Biol 2009 (Rhinitis, Allergic, Perennial...) : In contrast with the other HB-epidermal growth factor sheddases, ADAM-10 and -17, TNF-alpha in vitro increased the expression of ADAM-12 by AEC, an effect amplified by IL-4 and IL-13
Baertling et al., Brain Res 2010 (Demyelinating Diseases...) : It appears that LPS- and TNFalpha induced ADAM12 expression is mediated via the classic NFkappaB pathway