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AKR1C3 — INS
Text-mined interactions from Literome
Du et al., J Clin Endocrinol Metab 2009
:
Insulin increased KLF15 mRNA expression according to real-time RT-PCR and
increased HSD17B5 promoter activity according to luciferase assays
Dozmorov et al., BMC cancer 2010
(Disease Progression...) :
Microarray and bioinformatics analysis suggested that overexpression of
AKR1C3 in PC-3 cells modulates estrogen and androgen metabolism,
activates insulin-like growth factor (IGF)-1 and Akt signaling pathways, as well as promotes tumor angiogenesis and aggressiveness