Gene interactions and pathways from curated databases and text-mining

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AKT1 — CCR7

Text-mined interactions from Literome

Riol-Blanco et al., J Immunol 2005 (MAP Kinase Signaling System) : CCR7 induced activation of PI3K/Akt ; however, these enzymes did not regulate either chemotaxis or the speed of DCs
Liu et al., Mol Immunol 2007 : Further studies show that the triptolide mediated inhibitory effects of LPS induced activation of phosphatidylinositol-3 kinase (PI3-K)/Akt and nuclear NF-kappaB activation are involved in down-regulation of COX-2 and CCR7 expression resulting in impaired migration to secondary lymphoid organs of DC
Xu et al., PloS one 2011 (Carcinoma, Non-Small-Cell Lung...) : The CCL21/CCR7 interaction significantly enhanced phosphorylation of extracellular signal regulated kinase ( P-ERK ) but not Akt , as measured by Western blot