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BCAP31 — CASP8

Pathways - manually collected, often from reviews:

• Reactome Reaction: BCAP31 → CASP8 (reaction) Breckenridge et al., J Cell Biol 2003*

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: BCAP31 — CASP8 (physical association, affinity chromatography technology) Iwasawa et al., EMBO J 2011*
• IRef Biogrid Interaction: BCAP31 — CASP8 (direct interaction, enzymatic study) Chandra et al., Mol Cell Biol 2004*
• IRef Biogrid Interaction: BCAP31 — CASP8 (physical association, affinity chromatography technology) Breckenridge et al., Proc Natl Acad Sci U S A 2002*
• IRef Biogrid Interaction: BCAP31 — CASP8 (colocalization, biochemical) Breckenridge et al., Proc Natl Acad Sci U S A 2002*
• IRef Biogrid Interaction: BCAP31 — CASP8 (direct interaction, enzymatic study) Ng et al., J Cell Biol 1997*
• IRef Biogrid Interaction: BCAP31 — CASP8 (physical association, affinity chromatography technology) Ng et al., J Cell Biol 1997*
• IRef Biogrid Interaction: BCAP31 — CASP8 (direct interaction, pull down) Ng et al., J Cell Biol 1997*
• IRef Hprd Interaction: CASP8 — BCAP31 (in vivo) Breckenridge et al., J Cell Biol 2003*, Ng et al., J Cell Biol 1997*
• IRef Intact Interaction: Complex of FIS1-CASP8-BCAP31-FIS1-CASP8-BCAP31 (association, anti bait coimmunoprecipitation) Iwasawa et al., EMBO J 2011*
• IRef Intact Interaction: CASP8 — BCAP31 (physical association, anti bait coimmunoprecipitation) Iwasawa et al., EMBO J 2011*
• IRef Intact Interaction: CASP8 — BCAP31 (physical association, coimmunoprecipitation) Ng et al., J Cell Biol 1997*
• IRef Intact Interaction: BCAP31 — CASP8 (physical association, coimmunoprecipitation) Breckenridge et al., Proc Natl Acad Sci U S A 2002*
• IRef Ophid Interaction: CASP8 — BCAP31 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: CASP8 — BCAP31 (aggregation, confirmational text mining) Ng et al., J Cell Biol 1997*

Text-mined interactions from Literome

Chandra et al., Mol Cell Biol 2004 : Finally, we present evidence that the OMM localized active caspase 8 can activate cytosolic caspase 3 and ER-localized BAP31
Panaretakis et al., EMBO J 2009 : Early activation of the endoplasmic reticulum ( ER ) -sessile kinase PERK leads to phosphorylation of the translation initiation factor eIF2alpha, followed by partial activation of caspase-8 ( but not caspase-3 ), caspase-8 mediated cleavage of the ER protein BAP31 and conformational activation of Bax and Bak