Gene interactions and pathways from curated databases and text-mining

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BCL2 — CXCL2

Text-mined interactions from Literome

Karl et al., Cancer Res 2005 (Corneal Neovascularization) : Inhibition of Bcl-2 expression with small interfering RNA-Bcl-2, or the inhibition of Bcl-2 function with small molecule inhibitor BL-193, down-regulated CXCL8 and CXCL1 expression and caused marked decrease in the angiogenic potential of endothelial cells without affecting cell viability
Neiva et al., Neoplasia (New York, N.Y.) 2009 (Carcinoma, Squamous Cell) : Here, we observed that Bcl-2 signaling induces expression of IL-6, CXCL8 , and EGF, providing a mechanism for the upregulation of these cytokines in tumor associated endothelial cells