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BCL2 — RNF19A
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Qin et al., Free Radic Biol Med 2006
:
The effect of apocynin on apoptosis was associated with reduced
p38 MAPK activity,
increased Bcl-2 protein, and decreased Bax protein and caspase-3 activity
Tamma et al., J Leukoc Biol 2006
(MAP Kinase Signaling System) :
We further generated jacalin induced CD4+ T cell blasts, examined the effects of CD28XL, and observed enhanced up-regulation of
p38 and
activation of STAT-6, Bcl-2, and
Bcl-xL ... We further generated jacalin induced CD4+ T cell blasts, examined the effects of CD28XL, and observed enhanced up-regulation of
p38 and
activation of STAT-6,
Bcl-2 , and Bcl-xL
Kim et al., Apoptosis 2008
:
In conclusion, ACh prevented the hypoxia induced apoptosis of mouse ES cells by inhibiting the ROS mediated
p38 MAPK and JNK activation as well as the
regulation of
Bcl-2 , c-IAPs, and caspase-3
Zhang et al., International journal of molecular sciences 2012
:
Incubation of cultured endothelial cells of neonatal rats with ox-LDL for 24 h or infusion of ox-LDL in mice for 3 weeks led to the remarkable impairment of endothelial cells, including increased lactate dehydrogenase synthesis, phosphorylation of
p38 mitogen
activated protein kinases ( p38 MAPK ) and expression of apoptotic genes such as
B-cell leukemia/lymphoma 2 (Bcl-2) associated X protein ( Bax ) and caspase-3
Zhao et al., Brain Res 2013
(Brain Edema...) :
In addition, we found SB203580 significantly decreased
P-p38 MAPK levels, and
inhibited HPC induced mitochondria translocation of
Bcl-xL in the brain of HPC and MCAO treated mice