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BCL2 — TLR2
Text-mined interactions from Literome
Shi et al., J Biol Chem 2008
:
TLR signaling enhances the interaction of MyD88 and Trif with Beclin 1, and
reduces the binding of Beclin 1 to
Bcl-2 ... These findings indicate
TLR signaling via its adaptor proteins
reduces the binding of Beclin 1 to
Bcl-2 by recruiting Beclin 1 into the TLR signaling complex leading to autophagy
Chaturvedi et al., J Biol Chem 2010
(Tuberculosis) :
Taken together, our investigation identified PE_PGRS11 as an in vivo expressed immunodominant antigen that plays a crucial role in modulating cellular life span restrictions imposed during oxidative stress by triggering
TLR2 dependent expression of COX-2 and
Bcl2